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About Hemoglobin
Home / About Hemoglobin
What is Hemoglobin
The Oxygen Carrying Protein
Hemoglobin is found in the red blood cells (RBC) and is the actual protein component that carries oxygen in the blood stream.
Oxy-Rx™ is 1/5000 RBC's size, this stablizied hemoglobin can go throough obstructed blood vessels and end-size capillaries to supply oxygen to tissues in need.
Matinicus Pharma harvests blood from cows of traceable source, extract and ultra purify the heme out of the heme-o-globin protein with proprietary technology to carbohydrate and create lifesaving products which are universally compatible, portable and room-temperature stable.
The stabilized Heme-corbohydrate is kept in dry or liquid form.
Product Characteristics
- Delivers oxygen immediately upon infusion
- Long shelf life at liquid form
- 3 years at room temperature
- Shelf life in dry form, INDEFINITELY.
- Universally compatible. Non immunogenic.
- Small molecule (<1/5000th the size of a RBC)
- Low viscosity
In mammals, tissue oxygentation is regulated by a complex between the heart, the lungs and the circulating blood, which contains red blood cells suspended in plasma (the fluid part of blood). Oxygen is on-loaded into red blood cells in the lungs, transported throughout the body via the circulatory system, and off-loaded from red blood cells to tissues and organs.
Hemoglobin, a protein encapsulated within red blood cells, is the tetrameric (four-part) molecule responsible for carrying and releasing oxygen.
Oxy-Rx™ - "Natural" Modified-hemoglobin Protein Active Oxygen Carrier
Without product - stroke - brain damage
With product - continuous oxygen delivery - no brain damage
Oxy-Rx™ Characteristics
Hemoglobin | Bovine derived, Glutaraldehyde polymerized |
|---|---|
Appearance | Deep Purple |
Polymeric Product Average Molecular Weight | 250 kD |
pH | 7.6-7.9 |
Ion Concentration Na Cl K Ca | 145-160 mEq
105-120 mEq
3.5-5.5 mEq
0.5-1.5 mEq |
Osmolarity | 290-310 mOsm/Kg |
Hemoglobin Concentration | 13.0 g/dL |
Methemoglobin | <5% |
Endotoxin | <0.02 EU/mL |
Colloid Osmotic Pressure | 25 mmHg |
Viscosity (37° C) | 1.3 centipoise |
P50 | 38 mmHg |
Phospholipids | <0.1 mg/mL |
Reconstitution | None required |
Administration | Peripheral or central vein |
Storage requirements | Room temperature up to 37° C for three years |
For further information on OXY-Rx™ please contact us.
We would be happy to discuss it further.
0207 034 3300
We’d like to hear from you
Fitzrovia Hospital,
13-14 Fitzroy Square London, W1T 6AH
Please write to us
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